เผยแพร่ผลงานวิจัยของจักษุแพทย์ไทย ในจดหมายข่าว Academy Express

Academy Express เป็นจดหมายข่าว อิเล็กทรอนิกส์ ที่จัดทำโดย American Academy of Ophthalmology ส่งทาง email ทุกสัปดาห์ ถึงสมาชิกของ 19 องค์กร วิชาชีพทางจักษุวิทยาใน Asia Pacific region รวมทั้ง RCOPT ราชวิทยาลัยฯเชิญชวนสมาชิกจักษุแพทย์ ติดตาม ผลงานวิจัยของจักษุแพทย์ไทย ในคอลัมน์ ASIA PACIFIC JOURNAL STUDIES ในจดหมายข่าวดังกล่าว

ท่านสมาชิกจักษุแพทย์ที่มีผลงานวิจัยใหม่ในวารสารวิชาการทางจักษุวิทยาที่เป็น indexed journal ส่งผลงานเพื่อเผยแพร่ใน Academy Express ฉบับต่อไปได้ที่ yyosanan@gmail.com หรือ admin@rcopt.org

 

Academy Express ฉบับวันที่ 24 April 2021
Extended ILM peeling yields higher closure rate for full thickness macular hole 
Researchers compared 1- and 2-disc diameter conventional internal limiting membrane (ILM) peeling for large full thickness macular holes. The extended procedure led to a higher closure rate, particularly among patients with chronic full thickness macular holes for more than 6 months. However, visual outcomes were comparable in both groups. Eye, November 2020

https://pubmed.ncbi.nlm.nih.gov/33159177/

 

Academy Express ฉบับวันที่ 17 April 2021
IOP readings of edematous eyes appear to be lower with GAT than other tonometers 
Researchers assessed IOP of 60 patients with corneal edema after phacoemulsification using 4 different tonometers. Pressure reading with Goldmann applanation tonometry (GAT) tended to be lower than those obtained by the other tonometers, particularly the Tono-Pen. Caution should be used when interpreting GAT IOP readings of edematous corneas, the authors conclude. Journal of Glaucoma, October 2020

https://pubmed.ncbi.nlm.nih.gov/33137014/

 

Academy Express ฉบับวันที่ 10 April 2021
Early surgery and amblyopia treatment should be considered for childhood glaucoma 
This retrospective study identified prognostic factors for poor visual outcomes in 45 glaucomatous eyes of children 4 years or younger. Approximately 64% of eyes had poor visual acuity, often due to deprivation amblyopia. Prognostic factors for poor vision included secondary glaucoma, a diagnosis at 3 months or younger, and an interval of 3 months or longer before surgery. Journal of Pediatric Ophthalmology & Strabismus, September 2020

https://pubmed.ncbi.nlm.nih.gov/32956477/

Academy Express ฉบับวันที่ 3 April 2021
Endogenous endophthalmitis yields poor visual outcomes even after treatment 
This retrospective study describes 29 eyes with endogenous endophthalmitis. The most common causative organism was Streptococcus spp. Positive vitreous cultures were significantly tied to unfavorable visual outcomes. Even with early treatment, the rate of evisceration and enucleation remained high. Journal of Ophthalmology, December 2020

https://pubmed.ncbi.nlm.nih.gov/33489338/

Academy Express ฉบับวันที่ 27 March 2021
Retained IOFB linked to poor outcomes in post-traumatic endophthalmitis 
Researchers report prognostic factors for poor visual outcomes in 66 patients with post-traumatic endophthalmitis after open globe injury. Analysis revealed that a retained intraocular foreign body was significantly linked to poor visual outcomes. Most cases were caused by gram-positive organisms, particularly Bacillus cereus. International Journal of Ophthalmology, December 2020

https://pubmed.ncbi.nlm.nih.gov/33344198/

Academy Express ฉบับวันที่ 20 March 2021
Baseline vision, steroid treatment affected visual outcomes in NMOSD-ON 
This retrospective study identified prognostic factors for visual outcomes after the first episode of neuroretinitis optica spectrum disorder-related optic neuritis (NMOSD-ON). Assessment of 63 eyes revealed that a baseline BCVA of counting fingers or better and intravenous methylprednisolone treatment within 21 days of symptom onset were factors for good visual outcomes. Clinical Ophthalmology, December 2020

https://pubmed.ncbi.nlm.nih.gov/33304093/

Academy Express ฉบับวันที่ 13 March 2021
Recurrent Vogt-Koyanagi-Harada disease linked to altered choroidal volume 
The authors examined 3D choroidal volume changes in patients with recurrent Vogt-Konayagi-Harada disease. Using enhanced depth imaging OCT, they found alterations choroidal volume during the recurrent stage of disease, even in an absence of anterior segment inflammation. The findings suggest central choroidal volume may serve as a biomarker for detecting choroidal morphological change in this patient population. Current Eye Research, November 2020

https://pubmed.ncbi.nlm.nih.gov/33215546/

Academy Express ฉบับวันที่ 6 March 2021
Patients with MOG-IgG optic neuritis tend to have better visual outcomes 
A new study describes the clinical characteristics and long-term visual outcomes of optic neuritis in Thailand. Researchers assessed 28 eyes with MOG-IgG optic neuritis and 59 with AQP4-IgG optic neuritis during an 11-year period. Patients with MOG-IgG disease tend to present with bilaterality and optic disc edema and have better visual outcomes compared with patients with AQP4-IgG disease. Clinical Ophthalmology, November 2020

https://pubmed.ncbi.nlm.nih.gov/33273804/

Academy Express ฉบับวันที่ 27 February 2021
Genetic polymorphisms tied to severe ocular complications in acetaminophen-related SJS/TEN 
The authors investigated the role of genetic polymorphism in 20 Thai patients with acetaminophen-related Steven-Johnson (SJS)/ toxic epidermal necrolysis (TEN). Within the cohort, severe ocular complications was strongly associated with human leucocyte antigen (HLA)-B*44:03 and moderately association with HLA-A*33:03 and HLA-C*07:01. British Journal of Ophthalmology,

https://pubmed.ncbi.nlm.nih.gov/33229345/

 

Academy Express ฉบับวันที่ 20 February 2021
Vitrectomy provides favorable anatomical success in AIDS patients with retinal detachment 
This analysis evaluates outcomes in 45 patients (52 eyes) with AIDS undergoing vitrectomy for cytomegalovirus retinitis-related retinal detachment. Over a mean follow-up of 42 months, primary anatomical success was achieved in 86% of eyes and 65% had a VA of 20/200 or better. The use of highly active antiretroviral therapy prior to surgery and early vitrectomy increased the probability of achieving both anatomical and VA success. Medicine (Baltimore), October 2020

https://pubmed.ncbi.nlm.nih.gov/33120835/

Academy Express ฉบับวันที่ 13 February 2021
PFCL use can yield satisfactory retinal reattachment 
A new study describes the outcomes of retinal detachment repair by vitrectomy and perfluorocarbon liquid (PFCL) tamponade. Among 122 study eyes, short- to medium-term PFCL tamponade achieved a high satisfaction rate. Post-operative hypotony was a predictor for unfavorable visual and anatomical outcomes. BMC Ophthalmology, September 2020

https://pubmed.ncbi.nlm.nih.gov/32873279/

Academy Express ฉบับวันที่ 6 February 2021
Characterization of HIV-associated optic neuritis 
These findings suggest CD4 cell counts and viral load may help identify the type of acute optic neuritis (ON) in patients infected with HIV. Among 10 study patients, those with infectious ON had low initial CD4 counts and high viral loads while patients with noninfectious ON had increasing CD4 cell counts and undetectable HIV viral load after antiretroviral therapy. International Medical Case Reports Journal, November 2020

https://pubmed.ncbi.nlm.nih.gov/33204180/

Academy Express ฉบับวันที่ 30 January 2021
Some patients may benefit from using an eye drop guide for self-administering medication 
Researchers describe the usefulness of an eye drop guide device for self-administering glaucoma medication. After 4 to 6 months, approximately 19% of 57 patients used the guide everyday while 46% never used it. The findings suggest an eye drop guide is most effective for patients using only 1 medication administered in a standing or sitting position. Clinical Ophthalmology, November 2020

https://pubmed.ncbi.nlm.nih.gov/33177804/

Academy Express ฉบับวันที่ 23 January 2021
Glycerin-preserved corneoscleral patch grafts effective for GDD implantation 
This study investigates outcomes for glycerin-preserved human-donor corneoscleral tissue as the patch graft for glaucoma drainage device (GDD) implantation. Among 102 glaucoma patients, the 5-year survival rate of the corneoscleral graft was 96%. The patch graft-related complications were comparable to other materials Journal of Glaucoma, November 2020

https://pubmed.ncbi.nlm.nih.gov/32890110/

 

Academy Express ฉบับวันที่ 16 January 2021

CMET can lead to cornea-like epithelium in successful cases 
A 13-patient study suggests successful autologous cultivated oral mucosal epithelial transplantation (COMET) can lead to a predominant cornea-like epithelium at long-term follow-up. Failed cases had a mainly conjunctival phenotype. However, all eyes had evidence of oral mucosal epithelial cells. Cornea, October 2020

https://pubmed.ncbi.nlm.nih.gov/33079916/

 

Academy Express ฉบับวันที่ 9 January 2021
Advanced stage presentation hinders effective management of retinoblastoma 
This retrospective study assessed whether new therapeutic approaches have improved clinical outcomes in patients with retinoblastoma in Thailand. Medical records of patients treated at a single hospital revealed that survival rates and globe-saving rates appear to have improved but advanced stage presentation remained the major obstacle. Pediatric International, October 2020

https://pubmed.ncbi.nlm.nih.gov/33022851/